| DC Field | Value | Language |
|---|---|---|
| dc.contributor | Department of Applied Biology and Chemical Technology | en_US |
| dc.creator | Yuen, OY | en_US |
| dc.creator | So, CM | en_US |
| dc.date.accessioned | 2021-05-13T08:31:42Z | - |
| dc.date.available | 2021-05-13T08:31:42Z | - |
| dc.identifier.issn | 1433-7851 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10397/89844 | - |
| dc.language.iso | en | en_US |
| dc.publisher | Wiley-VCH | en_US |
| dc.subject | Arylation | en_US |
| dc.subject | Cross-coupling | en_US |
| dc.subject | Ketones | en_US |
| dc.subject | Ligand design | en_US |
| dc.subject | Synthetic methods | en_US |
| dc.title | Ligand control of palladium-catalyzed site-selective α- and γ-Arylation of α,β-Unsaturated Ketones with (Hetero)aryl Halides | en_US |
| dc.type | Journal/Magazine Article | en_US |
| dc.identifier.spage | 23438 | en_US |
| dc.identifier.epage | 23444 | en_US |
| dc.identifier.volume | 59 | en_US |
| dc.identifier.issue | 52 | en_US |
| dc.identifier.doi | 10.1002/anie.202010682 | en_US |
| dcterms.abstract | This study describes the first palladium-catalyzed, site-selective α- and γ-arylation of α,β-unsaturated ketones with (hetero)aryl halides. A wide range of hetero(aryl)halides coupled with α,β-unsaturated ketones, and transformation into the arylated products proceeded with excellent to good yields. The site selectivity of the reaction is switchable by simply changing the phosphine ligand to access either α-arylated or γ-arylated products in good to excellent yields by using a low catalyst loading, and the method demonstrates good functional-group compatibility. | en_US |
| dcterms.bibliographicCitation | Angewandte chemie international edition, 21 Dec. 2020, v. 59, no. 52, p. 23438-23444 | en_US |
| dcterms.isPartOf | Angewandte chemie international edition | en_US |
| dcterms.issued | 2020-12-21 | - |
| dc.identifier.scopus | 2-s2.0-85096715149 | - |
| dc.identifier.pmid | 33007134 | - |
| dc.identifier.eissn | 1521-3773 | en_US |
| dc.description.validate | 202105 bchy | en_US |
| dc.description.oa | Not applicable | en_US |
| dc.identifier.FolderNumber | a0823-n01 | - |
| dc.identifier.SubFormID | 1963 | - |
| dc.description.fundingSource | RGC | en_US |
| dc.description.fundingSource | Others | en_US |
| dc.description.fundingText | RGC: 25301819 | en_US |
| dc.description.fundingText | Others: P0030376, P0030360 | en_US |
| Appears in Collections: | Journal/Magazine Article | |
Access
View full-text via PolyU eLinks 
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.