| Title: | Rhodium-catalyzed cross-coupling reaction of arylboronates and diazoesters and tandem alkylation reaction for the synthesis of quaternary alpha,alpha-heterodiaryl carboxylic esters | Authors: | Tsoi, YT Zhou, Z Yu, WY |
Issue Date: | 2011 | Source: | Organic letters, 2011, v. 13, no. 19, p. 5370-5373 | Abstract: | A rhodium-catalyzed one-pot three-component coupling reaction was developed for the synthesis of quaternary alpha,alpha-heterodiaryl carboxylic esters. This reaction involves cross-coupling of the arylrhodium(I) complexes with alpha-aryldiazoacetates to form oxa-pi-allylrhodium complexes. With KOfBu and alkyl halides, tandem alkylation of the allyl complex occurs to form a quaternary stereocenter at the carbenic carbon. | Publisher: | American Chemical Society | Journal: | Organic letters | ISSN: | 1523-7060 | EISSN: | 1523-7052 | DOI: | 10.1021/ol2022577 |
| Appears in Collections: | Journal/Magazine Article |
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